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Methods for the discovery of small molecules to monitor and perturb the activity of the human proteasome
Regulating protein production and degradation is critical to maintaining cellular homeostasis. The proteasome is a key player in keeping proteins at the proper levels. However, proteasome activity can be altered in certain disease states, such as blood cancers and neurodegenerative diseases. Cancers...
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| Опубликовано в: : | Future Med Chem |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Newlands Press Ltd
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7857359/ https://ncbi.nlm.nih.gov/pubmed/33275045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2020-0288 |
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