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Fluorescent Probes with Unnatural Amino Acids to Monitor Proteasome Activity in Real-Time

The proteasome is an essential protein complex that, when dysregulated, can result in various diseases in eukaryotic cells. As such, understanding the enzymatic activity of the proteasome and what can alter it is crucial to elucidating its roles in these diseases. This can be done effectively by usi...

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Podrobná bibliografie
Vydáno v:ACS Chem Biol
Hlavní autoři: Zerfas, Breanna L., Coleman, Rachel A., Salazar-Chaparro, Andres F., Macatangay, Nathaniel J., Trader, Darci J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8319958/
https://ncbi.nlm.nih.gov/pubmed/32786259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00634
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