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Establishment of A Suite of Assays That Support the Discovery of Proteasome Stimulators
BACKGROUND: The proteasome catalyzes the degradation of many mis-folded proteins, which are otherwise cytotoxic. There is interest in the discovery of proteasome agonists, but previous efforts to do so have been disappointing. METHODS: The cleavage of small fluorogenic peptides is used routinely as...
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| Publicado no: | Biochim Biophys Acta |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5366797/ https://ncbi.nlm.nih.gov/pubmed/28065760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2017.01.003 |
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