Genetic Ablation of G Protein-Gated Inwardly Rectifying K(+) Channels Prevents Training-Induced Sinus Bradycardia

Background: Endurance athletes are prone to bradyarrhythmias, which in the long-term may underscore the increased incidence of pacemaker implantation reported in this population. Our previous work in rodent models has shown training-induced sinus bradycardia to be due to microRNA (miR)-mediated tran...

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Pubblicato in:Front Physiol
Autori principali: Bidaud, Isabelle, D’Souza, Alicia, Forte, Gabriella, Torre, Eleonora, Greuet, Denis, Thirard, Steeve, Anderson, Cali, Chung You Chong, Antony, Torrente, Angelo G., Roussel, Julien, Wickman, Kevin, Boyett, Mark R., Mangoni, Matteo E., Mesirca, Pietro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Physiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7857143/
https://ncbi.nlm.nih.gov/pubmed/33551824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.519382
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