Amphiphilic Polyelectrolyte Graft Copolymers Enhance the Activity of Cyclic Dinucleotide STING Agonists

Cyclic dinucleotide (CDN) agonists of stimulator of interferon genes (STING) hold great therapeutic potential, but their activity is hindered by poor drug-like properties that restrict cytosolic bioavailability. Here, we address this challenge through the synthesis and evaluation of a novel series o...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Adv Healthc Mater
Main Authors: Nguyen, D. Chuong, Shae, Daniel, Pagendarm, Hayden M., Becker, Kyle W., Wehbe, Mohamed, Kilchrist, Kameron V., Pastora, Lucinda E., Palmer, Christian R., Seber, Pedro, Christov, Plamen P., Duvall, Craig L., Wilson, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7856189/
https://ncbi.nlm.nih.gov/pubmed/33225632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.202001056
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados