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Tetracyclines promote survival and fitness in mitochondrial disease models

Mitochondrial diseases (MD) are a heterogeneous group of disorders resulting from genetic mutations in nuclear or mitochondrial DNA (mtDNA) genes encoding for mitochondrial proteins (1,2). MD cause pathologies with severe tissue damage and ultimately death (3,4). There are no cures for MD and curren...

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Detalhes bibliográficos
Publicado no:Nat Metab
Main Authors: Perry, Elizabeth A., Bennett, Christopher F., Luo, Chi, Balsa, Eduardo, Jedrychowski, Mark, O’Malley, Katherine, Latorre-Muro, Pedro, Ladley, Richard Porter, Reda, Kamar, Wright, Peter M., Gygi, Steve P., Myers, Andrew G., Puigserver, Pere
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7856165/
https://ncbi.nlm.nih.gov/pubmed/33462515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42255-020-00334-y
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