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Structural Analysis of Prolines and Hydroxyprolines Binding to the L-glutamate-γ-semialdehyde Dehydrogenase Active Site of Bifunctional Proline Utilization A
Proline utilization A (PutA) proteins are bifunctional proline catabolic enzymes that catalyze the 4-electron oxidation of L-proline to L-glutamate using spatially-separated proline dehydrogenase and L-glutamate-γ-semialdehyde dehydrogenase (GSALDH, a.k.a. ALDH4A1) active sites. The observation that...
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| Gepubliceerd in: | Arch Biochem Biophys |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7856085/ https://ncbi.nlm.nih.gov/pubmed/33333077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2020.108727 |
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