Structural Analysis of Prolines and Hydroxyprolines Binding to the L-glutamate-γ-semialdehyde Dehydrogenase Active Site of Bifunctional Proline Utilization A

Proline utilization A (PutA) proteins are bifunctional proline catabolic enzymes that catalyze the 4-electron oxidation of L-proline to L-glutamate using spatially-separated proline dehydrogenase and L-glutamate-γ-semialdehyde dehydrogenase (GSALDH, a.k.a. ALDH4A1) active sites. The observation that...

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Publicado en:Arch Biochem Biophys
Main Authors: Campbell, Ashley C., Bogner, Alexandra N., Mao, Yizi, Becker, Donald F., Tanner, John J.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7856085/
https://ncbi.nlm.nih.gov/pubmed/33333077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2020.108727
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