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Competition for active TGFβ cytokine allows for selective retention of antigen-specific tissue resident memory T cells in the epidermal niche
Following antigen-driven expansion in lymph node, transforming growth factor-β (TGFβ) is required for differentiation of skin-recruited CD8(+) T cell effectors into epidermal resident memory T cells (Trm) and their epidermal persistence. We found that the source of TGFβ supporting Trm cells was auto...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Immunity |
|---|---|
| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7856016/ https://ncbi.nlm.nih.gov/pubmed/33212014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2020.10.022 |
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