General Light-Mediated, Highly Diastereoselective Piperidine Epimerization: From Most Accessible to Most Stable Stereoisomer

We report a combined photocatalytic and hydrogen atom transfer (HAT) approach for the light-mediated epimerization of readily accessible piperidines to provide the more stable diastereomer with high selectivity. The generality of the transformation was explored for a large variety of di- to tetrasub...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :J Am Chem Soc
Главные авторы: Shen, Zican, Walker, Morgan M., Chen, Shuming, Parada, Giovanny A., Chu, Duc M., Dongbang, Sun, Mayer, James M., Houk, K. N., Ellman, Jonathan A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855822/
https://ncbi.nlm.nih.gov/pubmed/33373212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c11911
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы