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Regio- and Diastereoselective Synthesis of Highly Substituted, Oxygenated Piperidines from Tetrahydropyridines

Diastereoselective epoxidation and regioselective ring-opening methods were developed for the synthesis of densely substituted, oxygenated piperidines from two classes of tetrahydropyridines with distinct stereochemical displays of functionalities. A new and practical in situ prepared epoxidation re...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Chen, Shuming, Mercado, Brandon Q., Bergman, Robert G., Ellman, Jonathan A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496584/
https://ncbi.nlm.nih.gov/pubmed/26098485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.5b00816
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