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New Regio- and Stereoselective Cascades via Unstabilized Azomethine Ylide Cycloadditions for the Synthesis of Highly Substituted Tropane and Indolizidine Frameworks

Multisubstituted tropanes and indolizidines have been prepared with high regio- and stereoselectivity by the [3 + 2] cycloaddition of unstabilized azomethine ylides generated from readily prepared trimethylsilyl substituted 1,2-dihydropyridines via protonation or alkylation followed by desilylation....

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Am Chem Soc
Päätekijät: Chen, Shuming, Bacauanu, Vlad, Knecht, Tobias, Mercado, Brandon Q., Bergman, Robert G., Ellman, Jonathan A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066814/
https://ncbi.nlm.nih.gov/pubmed/27642766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b08355
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