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Proteomics-Based Identification of DUB Substrates Using Selective Inhibitors
Deubiquitinating enzymes (DUBs) catalyze the removal of ubiquitin, thereby reversing the activity of E3 ubiquitin ligases and are central to the control of protein abundance and function. Despite the growing interest in DUBs as therapeutic targets, cellular functions for DUBs remain largely unknown...
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| Publicado no: | Cell Chem Biol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7855594/ https://ncbi.nlm.nih.gov/pubmed/33007217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2020.09.005 |
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