Proteomics-Based Identification of DUB Substrates Using Selective Inhibitors

Deubiquitinating enzymes (DUBs) catalyze the removal of ubiquitin, thereby reversing the activity of E3 ubiquitin ligases and are central to the control of protein abundance and function. Despite the growing interest in DUBs as therapeutic targets, cellular functions for DUBs remain largely unknown...

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Bibliografiske detaljer
Udgivet i:Cell Chem Biol
Main Authors: Bushman, Jonathan W., Donovan, Katherine A., Schauer, Nathan J., Liu, Xiaoxi, Hu, Wanyi, Varca, Anthony C., Buhrlage, Sara J., Fischer, Eric S.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855594/
https://ncbi.nlm.nih.gov/pubmed/33007217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2020.09.005
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