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Proteomic identification of tmRNA substrates

The tmRNA–SmpB system releases ribosomes stalled on truncated mRNAs and tags the nascent polypeptides to target them for proteolysis. In many species, mutations that disrupt tmRNA activity cause defects in growth or development. In Caulobacter crescentus cells lacking tmRNA activity there is a delay...

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Detalhes bibliográficos
Main Authors: Hong, Sue-Jean, Lessner, Faith H., Mahen, Elisabeth M., Keiler, Kenneth C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040454/
https://ncbi.nlm.nih.gov/pubmed/17940001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707671104
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