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Accelerating Post-SELEX Aptamer Engineering Using Exonuclease Digestion

The systematic evolution of ligands by exponential enrichment (SELEX) process enables the isolation of aptamers from random oligonucleotide libraries. However, it is generally difficult to identify the best aptamer from the resulting sequences, and the selected aptamers often exhibit suboptimal affi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Am Chem Soc
Päätekijät: Canoura, Juan, Yu, Haixiang, Alkhamis, Obtin, Roncancio, Daniel, Farhana, Rifat, Xiao, Yi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855447/
https://ncbi.nlm.nih.gov/pubmed/33378616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c09559
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