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Advances and Challenges in Small-Molecule DNA Aptamer Isolation, Characterization, and Sensor Development
Aptamers are short oligonucleotides isolated in vitro from randomized libraries that can bind to specific molecules with high affinity, and offer a number of advantages relative to antibodies as biorecognition elements in biosensors. However, it remains difficult and labor-intensive to develop aptam...
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| Veröffentlicht in: | Angew Chem Int Ed Engl |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8292151/ https://ncbi.nlm.nih.gov/pubmed/33559947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202008663 |
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