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Label-free profiling of DNA aptamer-small molecule binding using T5 exonuclease
In vitro aptamer isolation methods can yield hundreds of potential candidates, but selecting the optimal aptamer for a given application is challenging and laborious. Existing aptamer characterization methods either entail low-throughput analysis with sophisticated instrumentation, or offer the pote...
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| Publicat a: | Nucleic Acids Res |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7672472/ https://ncbi.nlm.nih.gov/pubmed/33053182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa849 |
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