Regulation of CEACAM5 and therapeutic efficacy of an anti-CEACAM5-SN38 antibody-drug conjugate in neuroendocrine prostate cancer

PURPOSE: Neuroendocrine prostate cancer (NEPC) is an aggressive form of castration-resistant prostate cancer (CRPC) for which effective therapies are lacking. We previously identified carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) as a promising NEPC cell surface antigen. Here w...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: DeLucia, Diana C., Cardillo, Thomas M., Ang, Lisa, Labrecque, Mark P., Zhang, Ailin, Hopkins, James E., De Sarkar, Navonil, Coleman, Ilsa, da Costa, Rui M. Gil, Corey, Eva, True, Lawrence D., Haffner, Michael C., Schweizer, Michael T., Morrissey, Colm, Nelson, Peter S., Lee, John K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854497/
https://ncbi.nlm.nih.gov/pubmed/33199493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-3396
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados