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Efficient Gene Suppression by DNA/DNA Double-Stranded Oligonucleotide In Vivo
We recently reported the antisense properties of a DNA/RNA heteroduplex oligonucleotide consisting of a phosphorothioate DNA-gapmer antisense oligonucleotide (ASO) strand and its complementary phosphodiester RNA/phosphorothioate 2′-O-methyl RNA strand. When α-tocopherol was conjugated with the compl...
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| Publicado no: | Mol Ther |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Gene & Cell Therapy
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7854292/ https://ncbi.nlm.nih.gov/pubmed/33290725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.10.017 |
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