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A High-throughput qPCR-based Method to Genotype the SOD1(G93A) Mouse Model for Relative Copy Number
The most commonly used mouse model in ALS preclinical research expresses multiple copies of the human SOD1 (G93A) transgene. During the course of breeding, successive generations of mice can lose copies of the transgene. Because shorter lifespan of these mice is dependent on transgene copy number, i...
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| Publicado en: | Bio Protoc |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Bio-Protocol
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7854241/ https://ncbi.nlm.nih.gov/pubmed/33654793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.3276 |
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