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A High-throughput qPCR-based Method to Genotype the SOD1(G93A) Mouse Model for Relative Copy Number
The most commonly used mouse model in ALS preclinical research expresses multiple copies of the human SOD1 (G93A) transgene. During the course of breeding, successive generations of mice can lose copies of the transgene. Because shorter lifespan of these mice is dependent on transgene copy number, i...
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| Publicado no: | Bio Protoc |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Bio-Protocol
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7854241/ https://ncbi.nlm.nih.gov/pubmed/33654793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.3276 |
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