Determination of lipoprotein(a) kringle repeat number from genomic DNA: copy number variation genotyping using qPCR

Plasma lipoprotein(a) [Lp(a)] concentration is related to risk of cardiovascular disease. The defining protein component of Lp(a) particles, apolipoprotein(a) [apo(a)], is encoded by the LPA gene. Apo(a) is extremely heterogeneous in size due to a common copy number variation, leading to a variable...

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Detalhes bibliográficos
Main Authors: Lanktree, Matthew B., Rajakumar, Chandheeb, Brunt, J. Howard, Koschinsky, Marlys L., Connelly, Philip W., Hegele, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
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Methods
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656671/
https://ncbi.nlm.nih.gov/pubmed/19060253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.D800050-JLR200
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