Accuracy in Copy Number Calling by qPCR and PRT: A Matter of DNA

The possible implication of copy number variation (CNV) in the genetic susceptibility to human disease needs to be assessed using robust methods that can be applied at a population scale. In this report, we analyze the performance of the two major techniques, quantitative PCR (qPCR) and paralog rati...

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Detalhes bibliográficos
Main Authors: Fernandez-Jimenez, Nora, Castellanos-Rubio, Ainara, Plaza-Izurieta, Leticia, Gutierrez, Galder, Irastorza, Iñaki, Castaño, Luis, Vitoria, Juan Carlos, Bilbao, Jose Ramon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236783/
https://ncbi.nlm.nih.gov/pubmed/22174923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028910
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