qKAT: a high-throughput qPCR method for KIR gene copy number and haplotype determination

Killer cell immunoglobulin-like receptors (KIRs), expressed on natural killer cells and T cells, have considerable biomedical relevance playing significant roles in immunity, pregnancy and transplantation. The KIR locus is one of the most complex and polymorphic regions of the human genome. Extensiv...

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Détails bibliographiques
Publié dans:Genome Med
Auteurs principaux: Jiang, W., Johnson, C., Simecek, N., López-Álvarez, M. R., Di, D., Trowsdale, J., Traherne, J. A.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
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Method
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041586/
https://ncbi.nlm.nih.gov/pubmed/27686127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-016-0358-0
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