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Copy number variation leads to considerable diversity for B but not A haplotypes of the human KIR genes encoding NK cell receptors

The KIR complex appears to be evolving rapidly in humans, and more than 50 different haplotypes have been described, ranging from four to 14 KIR loci. Previously it has been suggested that most KIR haplotypes consist of framework genes, present in all individuals, which bracket a variable number of...

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Detalhes bibliográficos
Main Authors: Jiang, Wei, Johnson, Chris, Jayaraman, Jyothi, Simecek, Nikol, Noble, Janelle, Moffatt, Miriam F., Cookson, William O., Trowsdale, John, Traherne, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460180/
https://ncbi.nlm.nih.gov/pubmed/22948769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.137976.112
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