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Estimating KIR Haplotype Frequencies on a Cohort of 10,000 Individuals: A Comprehensive Study on Population Variations, Typing Resolutions, and Reference Haplotypes

The killer cell immunoglobulin-like receptors (KIR) mediate human natural killer (NK) cell cytotoxicity via activating or inhibiting signals. Although informative and functional haplotype patterns have been reported, most genotyping has been performed at resolutions that are structurally ambiguous....

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Detalhes bibliográficos
Publicado no:PLoS One
Principais autores: Vierra-Green, Cynthia, Roe, David, Jayaraman, Jyothi, Trowsdale, John, Traherne, James, Kuang, Rui, Spellman, Stephen, Maiers, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056762/
https://ncbi.nlm.nih.gov/pubmed/27723813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163973
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