Estimating KIR Haplotype Frequencies on a Cohort of 10,000 Individuals: A Comprehensive Study on Population Variations, Typing Resolutions, and Reference Haplotypes

The killer cell immunoglobulin-like receptors (KIR) mediate human natural killer (NK) cell cytotoxicity via activating or inhibiting signals. Although informative and functional haplotype patterns have been reported, most genotyping has been performed at resolutions that are structurally ambiguous....

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Pubblicato in:PLoS One
Autori principali: Vierra-Green, Cynthia, Roe, David, Jayaraman, Jyothi, Trowsdale, John, Traherne, James, Kuang, Rui, Spellman, Stephen, Maiers, Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056762/
https://ncbi.nlm.nih.gov/pubmed/27723813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163973
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