Efficient Sequencing, Assembly, and Annotation of Human KIR Haplotypes

The homology, recombination, variation, and repetitive elements in the natural killer-cell immunoglobulin-like receptor (KIR) region has made full haplotype DNA interpretation impossible in a high-throughput workflow. Here, we present a new approach using long-read sequencing to efficiently capture,...

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Detalles Bibliográficos
Publicado en:Front Immunol
Autores principales: Roe, David, Williams, Jonathan, Ivery, Keyton, Brouckaert, Jenny, Downey, Nick, Locklear, Chad, Kuang, Rui, Maiers, Martin
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581912/
https://ncbi.nlm.nih.gov/pubmed/33162997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.582927
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