A Detailed View of KIR Haplotype Structures and Gene Families as Provided by a New Motif-Based Multiple Sequence Alignment

Human chromosome 19q13.4 contains genes encoding killer-cell immunoglobulin-like receptors (KIR). Reported haplotype lengths range from 67 to 269 kb and contain 4 to 18 genes. The region has certain properties such as single nucleotide variation, structural variation, homology, and repetitive elemen...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Roe, David, Vierra-Green, Cynthia, Pyo, Chul-Woo, Geraghty, Daniel E., Spellman, Stephen R., Maiers, Martin, Kuang, Rui
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708349/
https://ncbi.nlm.nih.gov/pubmed/33312175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.585731
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