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Accurate and Efficient KIR Gene and Haplotype Inference From Genome Sequencing Reads With Novel K-mer Signatures

The killer-cell immunoglobulin-like receptor (KIR) proteins evolve to fight viruses and mediate the body’s reaction to pregnancy. These roles provide selection pressure for variation at both the structural/haplotype and base/allele levels. At the same time, the genes have evolved relatively recently...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Roe, David, Kuang, Rui
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7727328/
https://ncbi.nlm.nih.gov/pubmed/33324401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.583013
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