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Indexing Arbitrary-Length k-Mers in Sequencing Reads

We propose a lightweight data structure for indexing and querying collections of NGS reads data in main memory. The data structure supports the interface proposed in the pioneering work by Philippe et al. for counting and locating k-mers in sequencing reads. Our solution, PgSA (pseudogenome suffix a...

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Vydáno v:PLoS One
Hlavní autoři: Kowalski, Tomasz, Grabowski, Szymon, Deorowicz, Sebastian
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504488/
https://ncbi.nlm.nih.gov/pubmed/26182400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133198
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