Influence of KIR gene copy number on natural killer cell education

Natural killer (NK) cells are functionally tuned by education via killer cell immunoglobulin receptors (KIRs) interacting with HLA class I molecules. We examined the effect of KIR gene copy number variation on the education of human NK cells. The frequency of NK cells expressing a given KIR correlat...

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Detalhes bibliográficos
Main Authors: Béziat, Vivien, Traherne, James A., Liu, Lisa L., Jayaraman, Jyothi, Enqvist, Monika, Larsson, Stella, Trowsdale, John, Malmberg, Karl-Johan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674669/
https://ncbi.nlm.nih.gov/pubmed/23637128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-10-461442
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