NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs

Human natural killer (NK) cells are functionally regulated by killer cell immunoglobulin-like receptors (KIRs) and their interactions with HLA class I molecules. As KIR expression in a given NK cell is genetically hard-wired, we hypothesized that KIR repertoire perturbations reflect expansions of un...

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Hlavní autoři: Béziat, Vivien, Liu, Lisa L., Malmberg, Jenny-Ann, Ivarsson, Martin A., Sohlberg, Ebba, Björklund, Andreas T., Retière, Christelle, Sverremark-Ekström, Eva, Traherne, James, Ljungman, Per, Schaffer, Marie, Price, David A., Trowsdale, John, Michaëlsson, Jakob, Ljunggren, Hans-Gustaf, Malmberg, Karl-Johan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2013
Témata:
Immunobiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617633/
https://ncbi.nlm.nih.gov/pubmed/23325834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-10-459545
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