NK cells expressing inhibitory KIR for non–self-ligands remain tolerant in HLA-matched sibling stem cell transplantation

Natural killer (NK)–cell alloreactivity in recipients of hematopoietic stem cell grafts from HLA-identical siblings is intriguing and has suggested breaking of NK-cell tolerance during the posttransplantation period. To examine this possibility, we analyzed clinical outcomes in a cohort of 105 patie...

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Detalhes bibliográficos
Main Authors: Björklund, Andreas T., Schaffer, Marie, Fauriat, Cyril, Ringdén, Olle, Remberger, Mats, Hammarstedt, Christina, Barrett, A. John, Ljungman, Per, Ljunggren, Hans-Gustaf, Malmberg, Karl-Johan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852367/
https://ncbi.nlm.nih.gov/pubmed/20097883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-229740
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