Improved outcome in HLA-identical sibling hematopoietic stem-cell transplantation for acute myelogenous leukemia predicted by KIR and HLA genotypes

Inhibitory killer immunoglobulin (Ig)-like receptors (KIRs) recognize HLA-C and -B epitopes on target cells, thereby regulating natural killer (NK) cell activity. In 178 patients receiving T-cell-depleted HLA-identical sibling transplants for acute myelogenous leukemia (AML), chronic myelogenous leu...

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Detalhes bibliográficos
Main Authors: Hsu, Katharine C., Keever-Taylor, Carolyn A., Wilton, Andrew, Pinto, Clara, Heller, Glenn, Arkun, Knarik, O'Reilly, Richard J., Horowitz, Mary M., Dupont, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2005
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1894998/
https://ncbi.nlm.nih.gov/pubmed/15731175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-12-4825
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