The graft-versus-leukemia effect using matched unrelated donors is not superior to HLA-identical siblings for hematopoietic stem cell transplantation

Do some patients benefit from an unrelated donor (URD) transplant because of a stronger graft-versus-leukemia (GVL) effect? We analyzed 4099 patients with acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), and chronic myeloid leukemia (CML) undergoing a myeloablative allogeneic hemato...

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Autors principals: Ringdén, Olle, Pavletic, Steven Z., Anasetti, Claudio, Barrett, A. John, Wang, Tao, Wang, Dan, Antin, Joseph H., Di Bartolomeo, Paolo, Bolwell, Brian J., Bredeson, Christopher, Cairo, Mitchell S., Gale, Robert P., Gupta, Vikas, Hahn, Theresa, Hale, Gregory A., Halter, Jorg, Jagasia, Madan, Litzow, Mark R., Locatelli, Franco, Marks, David I., McCarthy, Philip L., Cowan, Morton J., Petersdorf, Effie W., Russell, James A., Schiller, Gary J., Schouten, Harry, Spellman, Stephen, Verdonck, Leo F., Wingard, John R., Horowitz, Mary M., Arora, Mukta
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2009
Matèries:
Transplantation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662650/
https://ncbi.nlm.nih.gov/pubmed/19059878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-07-163212
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