The graft-versus-leukemia effect using matched unrelated donors is not superior to HLA-identical siblings for hematopoietic stem cell transplantation

Do some patients benefit from an unrelated donor (URD) transplant because of a stronger graft-versus-leukemia (GVL) effect? We analyzed 4099 patients with acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), and chronic myeloid leukemia (CML) undergoing a myeloablative allogeneic hemato...

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Hlavní autoři: Ringdén, Olle, Pavletic, Steven Z., Anasetti, Claudio, Barrett, A. John, Wang, Tao, Wang, Dan, Antin, Joseph H., Di Bartolomeo, Paolo, Bolwell, Brian J., Bredeson, Christopher, Cairo, Mitchell S., Gale, Robert P., Gupta, Vikas, Hahn, Theresa, Hale, Gregory A., Halter, Jorg, Jagasia, Madan, Litzow, Mark R., Locatelli, Franco, Marks, David I., McCarthy, Philip L., Cowan, Morton J., Petersdorf, Effie W., Russell, James A., Schiller, Gary J., Schouten, Harry, Spellman, Stephen, Verdonck, Leo F., Wingard, John R., Horowitz, Mary M., Arora, Mukta
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2009
Témata:
Transplantation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662650/
https://ncbi.nlm.nih.gov/pubmed/19059878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-07-163212
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