Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis

Enhancer of zeste homolog 2 (EZH2), a key histone methyltransferase and EMT inducer, is overexpressed in diverse carcinomas, including breast cancer. However, the molecular mechanisms of EZH2 dysregulation in cancers are still largely unknown. Here, we discover that EZH2 is asymmetrically dimethylat...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell Death Differ
Asıl Yazarlar: Li, Zhongwei, Wang, Diandian, Lu, Jun, Huang, Baiqu, Wang, Yibo, Dong, Meichen, Fan, Dongmei, Li, Hongyuan, Gao, Yanyan, Hou, Pingfu, Li, Minle, Liu, Hui, Pan, Zhen-Qiang, Zheng, Junnian, Bai, Jin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7853151/
https://ncbi.nlm.nih.gov/pubmed/32895488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00615-9
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller