Arginine methylation of SHANK2 by PRMT7 promotes human breast cancer metastasis through activating endosomal FAK signalling

Arginine methyltransferase PRMT7 is associated with human breast cancer metastasis. Endosomal FAK signalling is critical for cancer cell migration. Here we identified the pivotal roles of PRMT7 in promoting endosomal FAK signalling activation during breast cancer metastasis. PRMT7 exerted its functi...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Liu, Yingqi, Li, Lingling, Liu, Xiaoqing, Wang, Yibo, Liu, Lingxia, Peng, Lu, Liu, Jiayuan, Zhang, Lian, Wang, Guannan, Li, Hongyuan, Liu, Dong-Xu, Huang, Baiqu, Lu, Jun, Zhang, Yu
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2020
Assuntos:
Cancer Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494359/
https://ncbi.nlm.nih.gov/pubmed/32844749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.57617
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