Arginine methylation of SHANK2 by PRMT7 promotes human breast cancer metastasis through activating endosomal FAK signalling

Arginine methyltransferase PRMT7 is associated with human breast cancer metastasis. Endosomal FAK signalling is critical for cancer cell migration. Here we identified the pivotal roles of PRMT7 in promoting endosomal FAK signalling activation during breast cancer metastasis. PRMT7 exerted its functi...

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Publicado en:eLife
Autores principales: Liu, Yingqi, Li, Lingling, Liu, Xiaoqing, Wang, Yibo, Liu, Lingxia, Peng, Lu, Liu, Jiayuan, Zhang, Lian, Wang, Guannan, Li, Hongyuan, Liu, Dong-Xu, Huang, Baiqu, Lu, Jun, Zhang, Yu
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cancer Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494359/
https://ncbi.nlm.nih.gov/pubmed/32844749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.57617
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