The degradation of EZH2 mediated by lncRNA ANCR attenuated the invasion and metastasis of breast cancer

EZH2 (the Enhancer of Zeste Homolog 2), as a key epigenetic regulator and EMT inducer, participates in a variety of cancer metastasis. EZH2 stability is regulated by several types of post-translational modifications (PTMs).The long non-coding RNAs (lncRNA) have been implicated to have critical roles...

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Bibliografiske detaljer
Udgivet i:Cell Death Differ
Main Authors: Li, Zhongwei, Hou, Pingfu, Fan, Dongmei, Dong, Meichen, Ma, Musong, Li, Hongyuan, Yao, Ruosi, Li, Yuxin, Wang, Guannan, Geng, Pengyu, Mihretab, Adhanom, Liu, Dongxu, Zhang, Yu, Huang, Baiqu, Lu, Jun
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260507/
https://ncbi.nlm.nih.gov/pubmed/27716745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.95
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