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The Effect of Metformin vs Placebo on Sex Hormones in Canadian Cancer Trials Group MA.32

BACKGROUND: Metformin has been associated with lower breast cancer (BC) risk and improved outcomes in observational studies. Multiple biologic mechanisms have been proposed, including a recent report of altered sex hormones. We evaluated the effect of metformin on sex hormones in MA.32, a phase III...

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Bibliografiske detaljer
Udgivet i:J Natl Cancer Inst
Main Authors: Pimentel, Isabel, Chen, Bingshu E, Lohmann, Ana Elisa, Ennis, Marguerite, Ligibel, Jennifer, Shepherd, Lois, Hershman, Dawn L, Whelan, Timothy, Stambolic, Vuk, Mayer, Ingrid, Hobday, Timothy, Lemieux, Julie, Thompson, Alastair, Rastogi, Priya, Gelmon, Karen, Rea, Daniel, Rabaglio, Manuela, Ellard, Susan, Mates, Mihaela, Bedard, Philippe, Pitre, Lacey, Vandenberg, Theodore, Dowling, Ryan J O, Parulekar, Wendy, Goodwin, Pamela J
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7850529/
https://ncbi.nlm.nih.gov/pubmed/33527137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djaa082
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