Effects of metformin versus placebo on Vitamin B12 metabolism in non-diabetic breast cancer patients in CCTG MA.32

BACKGROUND: Metformin is associated with low levels of vitamin B12 (VitB12) in patients with diabetes. The CCTG/MA.32 trial investigates effects of metformin vs placebo on breast cancer (BC) outcomes in non-diabetic high risk BC patients. We analyzed VitB12 at baseline and after 6 months of metformi...

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Publicado no:Breast Cancer Res Treat
Main Authors: Lohmann, Ana Elisa, Liebman, Mira F., Brien, William, Parulekar, Wendy R., Gelmon, Karen A., Shepherd, Lois E., Ligibel, Jennifer A., Hershman, Dawn L., Rastogi, Priya, Mayer, Ingrid A., Hobday, Timothy J., Lemieux, Julie, Thompson, Alastair Mark, Pritchard, Kathleen I., Whelan, Timothy Joseph, Mukherjee, Som D., Chalchal, Haji I., Bernstein, Vanessa, Stambolic, Vuk, Chen, Bingshu E., Goodwin, Pamela Jean
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798974/
https://ncbi.nlm.nih.gov/pubmed/28447237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-017-4265-x
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