Translation is required for miRNA‐dependent decay of endogenous transcripts

Post‐transcriptional repression of gene expression by miRNAs occurs through transcript destabilization or translation inhibition. mRNA decay is known to account for most miRNA‐dependent repression. However, because transcript decay occurs co‐translationally, whether target translation is a requireme...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Biasini, Adriano, Abdulkarim, Baroj, de Pretis, Stefano, Tan, Jennifer Y, Arora, Rajika, Wischnewski, Harry, Dreos, Rene, Pelizzola, Mattia, Ciaudo, Constance, Marques, Ana Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849302/
https://ncbi.nlm.nih.gov/pubmed/33300180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020104569
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