Translation is required for miRNA‐dependent decay of endogenous transcripts

Post‐transcriptional repression of gene expression by miRNAs occurs through transcript destabilization or translation inhibition. mRNA decay is known to account for most miRNA‐dependent repression. However, because transcript decay occurs co‐translationally, whether target translation is a requireme...

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Veröffentlicht in:EMBO J
Hauptverfasser: Biasini, Adriano, Abdulkarim, Baroj, de Pretis, Stefano, Tan, Jennifer Y, Arora, Rajika, Wischnewski, Harry, Dreos, Rene, Pelizzola, Mattia, Ciaudo, Constance, Marques, Ana Claudia
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849302/
https://ncbi.nlm.nih.gov/pubmed/33300180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020104569
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