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Translation is required for miRNA‐dependent decay of endogenous transcripts

Post‐transcriptional repression of gene expression by miRNAs occurs through transcript destabilization or translation inhibition. mRNA decay is known to account for most miRNA‐dependent repression. However, because transcript decay occurs co‐translationally, whether target translation is a requireme...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:EMBO J
Main Authors: Biasini, Adriano, Abdulkarim, Baroj, de Pretis, Stefano, Tan, Jennifer Y, Arora, Rajika, Wischnewski, Harry, Dreos, Rene, Pelizzola, Mattia, Ciaudo, Constance, Marques, Ana Claudia
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849302/
https://ncbi.nlm.nih.gov/pubmed/33300180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020104569
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