Gut microbiota-derived propionate mediates the neuroprotective effect of osteocalcin in a mouse model of Parkinson’s disease

BACKGROUND: Parkinson’s disease (PD) is a neurodegenerative disorder with no absolute cure. The evidence of the involvement of gut microbiota in PD pathogenesis suggests the need to identify certain molecule(s) derived from the gut microbiota, which has the potential to manage PD. Osteocalcin (OCN),...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Microbiome
Main Authors: Hou, Yan-fang, Shan, Chang, Zhuang, Si-yue, Zhuang, Qian-qian, Ghosh, Arijit, Zhu, Ke-cheng, Kong, Xiao-ke, Wang, Shu-min, Gong, Yan-ling, Yang, Yu-ying, Tao, Bei, Sun, Li-hao, Zhao, Hong-Yan, Guo, Xing-zhi, Wang, Wei-qing, Ning, Guang, Gu, Yan-yun, Li, Sheng-tian, Liu, Jian-min
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2021
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849090/
https://ncbi.nlm.nih.gov/pubmed/33517890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40168-020-00988-6
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