Gut microbiota-derived propionate mediates the neuroprotective effect of osteocalcin in a mouse model of Parkinson’s disease

BACKGROUND: Parkinson’s disease (PD) is a neurodegenerative disorder with no absolute cure. The evidence of the involvement of gut microbiota in PD pathogenesis suggests the need to identify certain molecule(s) derived from the gut microbiota, which has the potential to manage PD. Osteocalcin (OCN),...

詳細記述

保存先:
書誌詳細
出版年:Microbiome
主要な著者: Hou, Yan-fang, Shan, Chang, Zhuang, Si-yue, Zhuang, Qian-qian, Ghosh, Arijit, Zhu, Ke-cheng, Kong, Xiao-ke, Wang, Shu-min, Gong, Yan-ling, Yang, Yu-ying, Tao, Bei, Sun, Li-hao, Zhao, Hong-Yan, Guo, Xing-zhi, Wang, Wei-qing, Ning, Guang, Gu, Yan-yun, Li, Sheng-tian, Liu, Jian-min
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2021
主題:
Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849090/
https://ncbi.nlm.nih.gov/pubmed/33517890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40168-020-00988-6
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