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The Hepatocyte Clock and Feeding Control Chronophysiology of Multiple Liver Cell Types

Most cells of the body contain molecular clocks, but the requirement of peripheral clocks for rhythmicity, and their effects on physiology, are not well understood. Here we show that deletion of core clock components REV-ERBα and β in adult mouse hepatocytes disrupted diurnal rhythms of a subset of...

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Pubblicato in:Science
Autori principali: Guan, Dongyin, Xiong, Ying, Trinh, Trang Minh, Xiao, Yang, Hu, Wenxiang, Jiang, Chunjie, Dierickx, Pieterjan, Jang, Cholsoon, Rabinowitz, Joshua D., Lazar, Mitchell A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849028/
https://ncbi.nlm.nih.gov/pubmed/32732282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aba8984
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