The hepatic circadian clock fine-tunes the lipogenic response to feeding through RORα/γ

Liver lipid metabolism is under intricate temporal control by both the circadian clock and feeding. The interplay between these two mechanisms is not clear. Here we show that liver-specific depletion of nuclear receptors RORα and RORγ, key components of the molecular circadian clock, up-regulate exp...

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Dades bibliogràfiques
Publicat a:Genes Dev
Autors principals: Zhang, Yuxiang, Papazyan, Romeo, Damle, Manashree, Fang, Bin, Jager, Jennifer, Feng, Dan, Peed, Lindsey C., Guan, Dongyin, Sun, Zheng, Lazar, Mitchell A.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2017
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558923/
https://ncbi.nlm.nih.gov/pubmed/28747429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.302323.117
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