Selective inhibition of stemness through EGFR/FOXA2/SOX9 axis reduces pancreatic cancer metastasis

Pancreatic cancer (PC) is difficult to defeat due to mechanism (s) driving metastasis and drug resistance. Cancer stemness is a major challenging phenomenon associated with PC metastasis and limiting therapy efficacy. In this study, we evaluated the pre-clinical and clinical significance of eradicat...

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Publicado en:Oncogene
Autores principales: Kaushik, Garima, Seshacharyulu, Parthasarathy, Rauth, Sanchita, Nallasamy, Palanisamy, Rachagani, Satyanarayana, Nimmakayala, Rama Krishna, Vengoji, Raghupathy, Mallya, Kavita, Chirravuri-Venkata, Ramakanth, Singh, Amar B, Foster, Jason M., Ly, Quan P., Smith, Lynette M., Lele, Subodh M., Malafa, Mokenge P., Jain, Maneesh, Ponnusamy, Moorthy P., Batra, Surinder K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7848971/
https://ncbi.nlm.nih.gov/pubmed/33288882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01564-w
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