Synthetic protein conjugate vaccines provide protection against Mycobacterium tuberculosis in mice

The global incidence of tuberculosis remains unacceptably high, with new preventative strategies needed to reduce the burden of disease. We describe here a method for the generation of synthetic self-adjuvanted protein vaccines and demonstrate application in vaccination against Mycobacterium tubercu...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Hanna, Cameron C., Ashhurst, Anneliese S., Quan, Diana, Maxwell, Joshua W. C., Britton, Warwick J., Payne, Richard J.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2021
Témata:
Physical Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7848748/
https://ncbi.nlm.nih.gov/pubmed/33468674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2013730118
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