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Synthetic protein conjugate vaccines provide protection against Mycobacterium tuberculosis in mice

The global incidence of tuberculosis remains unacceptably high, with new preventative strategies needed to reduce the burden of disease. We describe here a method for the generation of synthetic self-adjuvanted protein vaccines and demonstrate application in vaccination against Mycobacterium tubercu...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hanna, Cameron C., Ashhurst, Anneliese S., Quan, Diana, Maxwell, Joshua W. C., Britton, Warwick J., Payne, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7848748/
https://ncbi.nlm.nih.gov/pubmed/33468674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2013730118
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