PLGA particulate subunit tuberculosis vaccines promote humoral and Th17 responses but do not enhance control of Mycobacterium tuberculosis infection

Tuberculosis places a staggering burden on human health globally. The new World Health Organisation End-TB Strategy has highlighted the urgent need for more effective TB vaccines to improve control of the disease. Protein-based subunit vaccines offer potential as safe and effective generators of pro...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ashhurst, Anneliese S., Parumasivam, Thaigarajan, Chan, John Gar Yan, Lin, Leon C. W., Flórido, Manuela, West, Nicholas P., Chan, Hak-Kim, Britton, Warwick J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5858788/
https://ncbi.nlm.nih.gov/pubmed/29554138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194620
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